Search results for "Mechanism based"
showing 10 items of 12 documents
A simulation of disagreement for control of rational cheating in peer review
2013
Understanding the peer review process could help research and shed light on the mechanisms that underlie crowdsourcing. In this paper, we present an agent-based model of peer review built on three entities - the paper, the scientist and the conference. The system is implemented on a BDI platform (Jason) that allows to define a rich model of scoring, evaluating and selecting papers for conferences. Then, we propose a programme committee update mechanism based on disagreement control that is able to remove reviewers applying a strategy aimed to prevent papers better than their own to be accepted (rational cheating). We analyze a homogeneous scenario, where all conferences aim to the same leve…
The Dynamic of Innovation Networks: A Switching Model on Technological Change
2012
In this paper we introduce an agent-based model with heterogeneous firms which compare their mutual innovation strategies on different network structures. By implementing a dynamic behavioral switching via a fitness mechanism based on agents performance, companies can endogenously modify their tactics of technological change and switch among three groups: stand-alone innovators, collaborative innovators and imitators. We focus the analysis on the impact of these three innovation categories on micro, meso and macro aggregates. Our findings show that collaborative companies are those having the highest positive impact on the economic system. Moreover, we study the properties of the emerging n…
Cell cycle: Aetiology of age-associated aneuploidy: a mechanism based on the 'free radical theory of ageing'
1995
A general model is put forward to explain the mechanism by which age-associated aneuploidies are produced. This is based on the free radical theory of ageing, which assumes a rise in oxidative stress with age. It is proposed that determination of indicators of oxidative stress in oocytes from various sources could be a first step in the testing of this hypothesis.
Enabling a win-win coexistence mechanism for WiFi and LTE in unlicensed bands
2018
The problem of WiFi and LTE coexistence has been significantly debated in the last years, with the emergence of LTE extensions enabling the utilization of unlicensed spectrum for carrier aggregation. Since the two technologies employ com-pletely different access protocols and frame transmission times, supporting coexistence with minimal modifications on existing protocols is not an easy task. Current solutions are often based on LTE unilateral adaptations, being LTE in unlicensed bands still under definition. In this paper, we demonstrate that it is possible to avoid a subordinated role for WiFi nodes, by simply equipping WiFi nodes with a sensing mechanism based on adaptive tunings of the …
Confinement, the gluon propagator and the interquark potential for heavy mesons
2012
The interquark static potential for heavy mesons described by a massive one-gluon exchange interaction obtained from the propagator of the truncated Dyson-Schwinger equations does not reproduced the expected Cornell potential. I show that no formulation based on a finite propagator will lead to confinement of quenched QCD. I propose a mechanism based on a singular nonperturbative coupling constant which has the virtue of giving rise to a finite gluon propagator and (almost) linear confinement. The mechanism can be slightly modified to produce the screened potentials of unquenched QCD.
Mechanism-based predictions of interactions.
1994
Abstract Exposure to more than one toxic compound is common in real life. The resulting toxic effects are often more than the simple sum of the effects of the individual compounds. It is unlikely that it will ever be possible to test all combinations. It is therefore highly desirable to improve or develop means for reasonably approximating predictions of interactions. In order to be valid and extrapolatable, these predictions are most promising if they are mechanism-based. Examples will be given for possibilities of mechanism-based predictions of interactions which exceed trivialities of simple increases by enzyme induction of enzymatic rates of a given biotransformation pathway leading to …
Evaluating activator-inhibitor mechanisms for sensors coordination
2007
The possibility to employ reaction-diffusion models to build spatial patterns in sensor networks has been advocated in other works. Nevertheless it has not been investigated how the biologically-inspired solutions perform in comparison to more traditional ones taking into account specificities of sensor networks like severe energy constraints. In this paper we present some preliminary results on the comparison between a biologically inspired coordination mechanism based on activator-inhibitor interaction and a simple mechanism, where nodes do not communicate but activate their sensing circuitry according to some probability.
Moving RTS/CTS to the frequency domain: an efficient contention scheme for 802.11ax networks
2019
In this paper, we propose a contention mechanism based on the execution of multiple contention rounds in the frequency domain (ReCHo), which is designed to offer high throughput performance and robustness with respect to imperfect carrier sensing. The main idea is using narrow tones as signalling messages for performing channel access contentions and allowing the Access Point (AP) to echo these signals, in order to extend the sensing capabilities to all the stations associated to the AP. In particular, we refer to the emerging IEEE 802.11ax standard, showing how our scheme can boost performance of random access with respect to the current version of IEEE 802.11ax OFDMA Back-Off (OBO), even …
Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project.
2010
The 6th European Framework Programme project LIINTOP was specifically raised to optimise and provide established protocols and experimental in vitro models for testing intestinal and liver absorption, metabolism and toxicity of molecules of pharmacological interest. It has been focused on some of the most promising existing liver and intestine in vitro models with the aim of further improving their performance and thus taking them to a pre-normative research stage. Regarding the specific area of the liver, a first basic approach was the optimisation of in vitro hepatic models and the development and optimisation of in vitro approaches for toxicity screening. New advanced technologies have b…
Causal complexity of new product development processes : a mechanism-based approach
2018
The outcomes of new product development (NPD) processes are dependent on the interplay of several interdependent activities. One product development activity can be dependent on the presence or absence of other activities, different kinds of NDP processes may lead to the same outcome, and specific kinds of activities may have a positive effect in one process but no effect in other processes. However, we currently lack means to examine and explain this causal complexity inherent in NPD processes. To address this issue, we introduce mechanism-based approach as a way to capture conjunctural and equifinal causal relations. We build this approach on the philosophical literature on mechanism-base…